Nurse Practitioners Salary — Port St. Lucie, Florida

The average Nurse Practitioners in Port St. Lucie, Florida earns $130,550 a year.

$130,550 / year, mean
↓ 5.6% below national average 68th percentile in Florida

Port St. Lucie sits roughly in the middle of the pack for this role within Florida — neither a standout nor a laggard. That's close to the national average for nurse practitioners — a fairly typical rate for this role. Cost of living here is close to the national average — not a major factor either way. This is a high-confidence estimate, based on a large sample of reported wages.

Percentile within Florida

0th 50th 100th
Employment (this metro)
410
Estimate confidence
RSE 1.7%
Cost of living 100 #57 most expensive of 188 cities in this dataset 100 = U.S. average · Source: BEA Regional Price Parities, 2024
Crime index 1340 #8 safest of 188 cities in this dataset Per 100k residents · Source: FBI Crime Data Explorer
Median home value $383,275 #61 priciest of 188 cities in this dataset Source: zillow_real
Median household income $72,506 #89 highest of 188 cities in this dataset Source: Census Bureau ACS 5-year

Combining these four figures gives a fuller picture than salary alone: Port St. Lucie ranks #57 for cost of living and #61 for home prices among the 188 cities in this pilot dataset, which matters as much as the headline salary number when comparing where to live.

San Jose $225,610 San Francisco $215,430 Vallejo $196,780 Napa $188,720 Modesto $187,690 Sacramento $177,260 Santa Rosa $172,330 Santa Maria $172,240 Riverside $171,680 Salinas $170,650 Hanford $170,070 Santa Cruz $170,020 San Luis Obispo $169,020 Fresno $167,690 Yuba City $167,630 Chico $166,540 Visalia $166,120 Bakersfield $165,290 San Diego $164,870 Los Angeles $163,610 Stockton $163,400 New York $162,620 El Centro $161,840 Salem $160,440 Portland $160,020 Redding $158,640 Merced $157,090 Longview $156,410 Eugene $156,230 Albany $155,140 Seattle $155,120 Kingston $154,030 Trenton $153,790 Mount Vernon $153,080 Bremerton $152,440 Oxnard $152,250 Kennewick $150,780 Medford $150,170 Wenatchee $149,860 Vineland $149,650 Midland $149,000 Ann Arbor $148,610 Bend $148,410 Olympia $148,070 Grants Pass $147,620 Bellingham $147,020 Kiryas Joel $146,490 Bay City $145,710 Binghamton $145,400 Spokane $145,170 Ithaca $143,840 Atlantic City $143,530 Charlottesville $142,830 Glens Falls $142,170 Corvallis $141,240 Philadelphia $139,700 Wildwood $139,610 Elmira $138,270 Killeen $138,100 Yakima $137,690 Beaumont $137,660 Corpus Christi $137,310 Detroit $137,290 Albany $136,720 Lancaster $136,290 Miami $136,150 Lebanon $135,650 Harrisburg $135,590 Watertown $135,170 Buffalo $135,110 Austin $135,000 Champaign $134,450 Utica $134,330 Allentown $134,150 Walla Walla $134,150 Baltimore $134,060 Reading $133,340 Jacksonville $133,260 Naples $133,130 San Antonio $133,090 Odessa $133,060 Chicago $133,040 Sarasota $133,020 Winchester $132,310 Houston $131,980 Waco $131,860 Kalamazoo $131,820 Syracuse $131,480 Longview $131,310 Tyler $131,310 Lansing $131,230 Crestview $131,050 Gainesville $131,030 York $130,950 Beckley $130,830 Texarkana $130,830 Port St. Lucie $130,550 Dallas $130,280 Salisbury $130,270 Indianapolis $130,150 College Station $130,080 Gettysburg $129,960 Victoria $129,870 Owensboro $129,790 Wichita Falls $129,460 El Paso $129,340 San Angelo $129,180 Orlando $128,860 Jackson $128,810 Elkhart $128,590 Charleston $128,430 Fort Myers $127,990 Brownsville $127,780 Dover $127,710 Staunton $127,630 Lexington $127,400 Laredo $127,390 Traverse City $127,390 Flint $127,350 Deltona $127,220 Rochester $127,190 Tampa $127,160 Columbus $127,140 Lubbock $127,020 Springfield $127,000 Bloomington $126,860 Sherman $126,830 Roanoke $126,720 Lafayette $126,710 Louisville $126,690 Niles $126,470 Peoria $126,280 Lynchburg $126,240 Morgantown $126,070 Bloomington $126,010 Battle Creek $125,960 Sebastian $125,920 Lexington Park $125,420 Michigan City $125,410 Saginaw $125,390 Ocala $125,250 Punta Gorda $125,120 Blacksburg $124,760 Amarillo $124,710 Kankakee $124,680 McAllen $124,580 Wheeling $124,500 Rockford $124,390 Terre Haute $124,250 South Bend $124,210 Williamsport $124,120 Abilene $124,080 Homosassa Springs $124,040 Huntington $123,640 Grand Rapids $123,610 Pittsburgh $123,580 Virginia Beach $123,580 Richmond $123,420 Harrisonburg $123,390 Fort Wayne $123,060 Paducah $122,990 Hagerstown $122,920 Parkersburg $122,640 State College $122,470 Lakeland $122,420 Pensacola $122,370 Kokomo $122,030 Weirton $121,750 Panama City $121,610 Decatur $121,300 Chambersburg $121,280 Scranton $121,110 Altoona $120,840 Elizabethtown $120,500 Bowling Green $120,120 Tallahassee $119,890 Muskegon $118,920 Evansville $118,790 Palm Bay $118,780 Erie $118,280 Monroe $117,250 Johnstown $115,900 Sebring $115,870 Muncie $115,220
CityMean salaryvs. Port St. Lucie
Abilene, Texas$124,080-5.0%
Albany, Oregon$155,140+18.8%
Albany, New York$136,720+4.7%
Allentown, Pennsylvania$134,150+2.8%
Altoona, Pennsylvania$120,840-7.4%
Amarillo, Texas$124,710-4.5%
Ann Arbor, Michigan$148,610+13.8%
Atlantic City, New Jersey$143,530+9.9%
Austin, Texas$135,000+3.4%
Bakersfield, California$165,290+26.6%
Baltimore, Maryland$134,060+2.7%
Battle Creek, Michigan$125,960-3.5%
Bay City, Michigan$145,710+11.6%
Beaumont, Texas$137,660+5.4%
Beckley, West Virginia$130,830+0.2%
Bellingham, Washington$147,020+12.6%
Bend, Oregon$148,410+13.7%
Binghamton, New York$145,400+11.4%
Blacksburg, Virginia$124,760-4.4%
Bloomington, Illinois$126,010-3.5%
Bloomington, Indiana$126,860-2.8%
Bowling Green, Kentucky$120,120-8.0%
Bremerton, Washington$152,440+16.8%
Brownsville, Texas$127,780-2.1%
Buffalo, New York$135,110+3.5%
Fort Myers, Florida$127,990-2.0%
Chambersburg, Pennsylvania$121,280-7.1%
Champaign, Illinois$134,450+3.0%
Charleston, West Virginia$128,430-1.6%
Charlottesville, Virginia$142,830+9.4%
Chicago, Illinois$133,040+1.9%
Chico, California$166,540+27.6%
College Station, Texas$130,080-0.4%
Columbus, Indiana$127,140-2.6%
Corpus Christi, Texas$137,310+5.2%
Corvallis, Oregon$141,240+8.2%
Crestview, Florida$131,050+0.4%
Dallas, Texas$130,280-0.2%
Decatur, Illinois$121,300-7.1%
Deltona, Florida$127,220-2.6%
Detroit, Michigan$137,290+5.2%
Dover, Delaware$127,710-2.2%
El Centro, California$161,840+24.0%
Elizabethtown, Kentucky$120,500-7.7%
Elkhart, Indiana$128,590-1.5%
Elmira, New York$138,270+5.9%
El Paso, Texas$129,340-0.9%
Erie, Pennsylvania$118,280-9.4%
Eugene, Oregon$156,230+19.7%
Evansville, Indiana$118,790-9.0%
Flint, Michigan$127,350-2.5%
Fort Wayne, Indiana$123,060-5.7%
Fresno, California$167,690+28.4%
Gainesville, Florida$131,030+0.4%
Gettysburg, Pennsylvania$129,960-0.5%
Glens Falls, New York$142,170+8.9%
Grand Rapids, Michigan$123,610-5.3%
Grants Pass, Oregon$147,620+13.1%
Hagerstown, Maryland$122,920-5.8%
Hanford, California$170,070+30.3%
Harrisburg, Pennsylvania$135,590+3.9%
Harrisonburg, Virginia$123,390-5.5%
Homosassa Springs, Florida$124,040-5.0%
Houston, Texas$131,980+1.1%
Huntington, West Virginia$123,640-5.3%
Indianapolis, Indiana$130,150-0.3%
Ithaca, New York$143,840+10.2%
Jackson, Michigan$128,810-1.3%
Jacksonville, Florida$133,260+2.1%
Johnstown, Pennsylvania$115,900-11.2%
Kalamazoo, Michigan$131,820+1.0%
Kankakee, Illinois$124,680-4.5%
Kennewick, Washington$150,780+15.5%
Killeen, Texas$138,100+5.8%
Kingston, New York$154,030+18.0%
Kiryas Joel, New York$146,490+12.2%
Kokomo, Indiana$122,030-6.5%
Lafayette, Indiana$126,710-2.9%
Lakeland, Florida$122,420-6.2%
Lancaster, Pennsylvania$136,290+4.4%
Lansing, Michigan$131,230+0.5%
Laredo, Texas$127,390-2.4%
Lebanon, Pennsylvania$135,650+3.9%
Lexington, Kentucky$127,400-2.4%
Lexington Park, Maryland$125,420-3.9%
Longview, Texas$131,310+0.6%
Longview, Washington$156,410+19.8%
Los Angeles, California$163,610+25.3%
Louisville, Kentucky$126,690-3.0%
Lubbock, Texas$127,020-2.7%
Lynchburg, Virginia$126,240-3.3%
McAllen, Texas$124,580-4.6%
Medford, Oregon$150,170+15.0%
Merced, California$157,090+20.3%
Miami, Florida$136,150+4.3%
Michigan City, Indiana$125,410-3.9%
Midland, Texas$149,000+14.1%
Modesto, California$187,690+43.8%
Monroe, Michigan$117,250-10.2%
Morgantown, West Virginia$126,070-3.4%
Mount Vernon, Washington$153,080+17.3%
Muncie, Indiana$115,220-11.7%
Muskegon, Michigan$118,920-8.9%
Napa, California$188,720+44.6%
Naples, Florida$133,130+2.0%
New York, New York$162,620+24.6%
Niles, Michigan$126,470-3.1%
Sarasota, Florida$133,020+1.9%
Ocala, Florida$125,250-4.1%
Odessa, Texas$133,060+1.9%
Olympia, Washington$148,070+13.4%
Orlando, Florida$128,860-1.3%
Owensboro, Kentucky$129,790-0.6%
Oxnard, California$152,250+16.6%
Paducah, Kentucky$122,990-5.8%
Palm Bay, Florida$118,780-9.0%
Panama City, Florida$121,610-6.8%
Parkersburg, West Virginia$122,640-6.1%
Pensacola, Florida$122,370-6.3%
Peoria, Illinois$126,280-3.3%
Philadelphia, Pennsylvania$139,700+7.0%
Pittsburgh, Pennsylvania$123,580-5.3%
Portland, Oregon$160,020+22.6%
Punta Gorda, Florida$125,120-4.2%
Reading, Pennsylvania$133,340+2.1%
Redding, California$158,640+21.5%
Richmond, Virginia$123,420-5.5%
Riverside, California$171,680+31.5%
Roanoke, Virginia$126,720-2.9%
Rochester, New York$127,190-2.6%
Rockford, Illinois$124,390-4.7%
Sacramento, California$177,260+35.8%
Saginaw, Michigan$125,390-4.0%
Salem, Oregon$160,440+22.9%
Salinas, California$170,650+30.7%
Salisbury, Maryland$130,270-0.2%
San Angelo, Texas$129,180-1.0%
San Antonio, Texas$133,090+1.9%
San Diego, California$164,870+26.3%
San Francisco, California$215,430+65.0%
San Jose, California$225,610+72.8%
San Luis Obispo, California$169,020+29.5%
Santa Cruz, California$170,020+30.2%
Santa Maria, California$172,240+31.9%
Santa Rosa, California$172,330+32.0%
Scranton, Pennsylvania$121,110-7.2%
Seattle, Washington$155,120+18.8%
Sebastian, Florida$125,920-3.5%
Sebring, Florida$115,870-11.2%
Sherman, Texas$126,830-2.8%
South Bend, Indiana$124,210-4.9%
Spokane, Washington$145,170+11.2%
Springfield, Illinois$127,000-2.7%
State College, Pennsylvania$122,470-6.2%
Staunton, Virginia$127,630-2.2%
Stockton, California$163,400+25.2%
Syracuse, New York$131,480+0.7%
Tallahassee, Florida$119,890-8.2%
Tampa, Florida$127,160-2.6%
Terre Haute, Indiana$124,250-4.8%
Texarkana, Texas$130,830+0.2%
Traverse City, Michigan$127,390-2.4%
Trenton, New Jersey$153,790+17.8%
Tyler, Texas$131,310+0.6%
Utica, New York$134,330+2.9%
Vallejo, California$196,780+50.7%
Victoria, Texas$129,870-0.5%
Vineland, New Jersey$149,650+14.6%
Virginia Beach, Virginia$123,580-5.3%
Visalia, California$166,120+27.2%
Waco, Texas$131,860+1.0%
Walla Walla, Washington$134,150+2.8%
Watertown, New York$135,170+3.5%
Weirton, West Virginia$121,750-6.7%
Wenatchee, Washington$149,860+14.8%
Wheeling, West Virginia$124,500-4.6%
Wichita Falls, Texas$129,460-0.8%
Wildwood, Florida$139,610+6.9%
Williamsport, Pennsylvania$124,120-4.9%
Winchester, Virginia$132,310+1.3%
Yakima, Washington$137,690+5.5%
York, Pennsylvania$130,950+0.3%
Yuba City, California$167,630+28.4%
Gross salary
130,550/yr
Estimated take-home
100,497/yr
Est. total withheld
23.0%

Single filer, federal income tax + FICA only, 2025 rates — Florida has no state income tax on wages. Does not include state-specific payroll withholdings beyond income tax (see Data transparency). Not tax advice — verify with a professional for your specific situation.

View cost of living in this state All Nurse Practitioners salaries in Florida → All Nurse Practitioners salaries →
Data transparency

Sources used for this page

Official occupation and area metadata behind the visible salary, cost, housing and safety signals.

Occupation 29-1171 SOC code
Official area Port St. Lucie, FL BLS metro/geographic area
Area code 38940 Stable geographic key
Reference year 2025 BLS OEWS
Cost: bea_realHousing: zillow_realCrime: latest availableNet-pay source: fl_constitucion_verificado 2025
No additional caveats are attached to this row.
Methodology

How this page is built

The salary figure is the mean annual wage reported by the BLS Occupational Employment and Wage Statistics (OEWS) program for this occupation and metro area. Percentile and national-average comparisons are calculated directly from the 188 cities currently in this dataset, not from a fixed external benchmark. Cost of living, crime and housing figures come from BEA, FBI and Zillow respectively — see "Data transparency" above for the exact sources and reference years used on this specific page.

Confidence: the RSE (relative standard error) shown under Overview indicates how reliable the salary estimate is for this metro — a lower RSE means a larger underlying sample.

On this page

Where this is

AK HI

Highlighted: Florida

Population (metro area)
506,701